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CO-methylating acetyl-CoA synthase
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CO-methylating acetyl-CoA synthase : ウィキペディア英語版
CO-methylating acetyl-CoA synthase

Acetyl-CoA Synthase (ACS), not to be confused with Acetyl-CoA Synthetase or Acetate-CoA Ligase (ADP forming), is a Nickel containing enzyme involved in the metabolic processes of cells. Together with Carbon monoxide dehydrogenase (CODH), it forms the bifunctional enzyme Acetyl-CoA Synthase/Carbon Monoxide Dehydrogenase (ACS/CODH) found in anaerobic organisms such as archaea and eubacteria. The ACS/CODH enzyme works primarily through the Wood–Ljungdahl pathway which converts Carbon dioxide to Acetyl-CoA. Another name for this enzyme is CO-methylating acetyl-CoA synthase.
==Chemistry==

In nature, there are six different pathways where CO is fixed. Of these, the Wood–Ljungdahl pathway is the predominant sink in anaerobic conditions. Acetyl-CoA Synthase (ACS) and carbon monoxide dehydrogenase (CODH) are integral enzymes in this one pathway and can perform diverse reactions in the carbon cycle as a result. Because of this, the exact activity of these molecules has come under intense scrutiny over the past decade.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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